Scientists have suggested how an organic molecule affects bacteria that are resistant to drugs and have found that it can suppress and destroy a pathogen that can cause significant illness or, in some circumstances, death. The findings of the study have been published in the journal Antibiotics. Pseudomonas aeruginosa is a type of bacteria commonly found in hospitalized patients that can lead to infections in the blood, lungs (pneumonia) or other parts of the body after surgery. Hydroquinine, an organic compound found in the bark of some trees, was recently found to have bactericidal activity against the germ and several other clinically important bacteria, including Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae. The team behind the discovery, from the University of Portsmouth and the Naresuan and Pibulsongkram Rajabhat Universities in Thailand, has now investigated the molecular responses of Pseudomonas aeruginosa strains to hydrokinin. They did this by looking at which genes were turned on and which were turned off in response to the drug.
Source link
